Interferons (IFNs) were the first family of cytokines to be discovered. In 1957 researchers observed that if susceptible animal cells were exposed to a colonizing virus, these cells immediately become resistant to attack by other viruses. This resistance was induced by a substance secreted by virally-infected cells, which was named ‘interferon’ (IFN). Subsequently it has been shown that most species actually produce a whole range of interferons. Discovered over 50 years ago, the interferons (IFNs) were first identified and are historically best known for their ability to elicit viral resistance to cells.
Types of Interferons
Original Youtube video here: Learn More About Why We Have Cell Receptors